Combining 3D Cell Culture Chemosensitivity Results and NGS Profiles to Maximize Outcomes in Glioblastoma

High Grade Glioma (HGG) Functional Precision Medicine—A Six Webinar Series

Virtual 60-minute webinar featuring expert discussion of real world HGG patient cases.

SESSION 4 of 6

Date Recorded:

February 22, 2024
Recording Length:

54:11
Topics:

high grade glioma, Kiyatec

For this fourth installment of a six-webinar series, join us to hear how Dr. Odia of the Miami Cancer Institute at Baptist Health South Florida is using 3D Cell culture chemosensitivity results and NGS profiles to maximize outcomes in glioblastoma.

HGG patients have an extremely poor prognosis. Limited diagnostic tools are available to accurately predict treatment responses, leading to challenges in selecting effective therapeutic options. This interactive discussion will feature real world clinical cases, presented by Dr. Odia of the Miami Cancer Institute at Baptist Health South Florida, where a new functional precision oncology assay was used to direct therapy. There will be time for attendees to participate in interactive Q&A.

This Functional Precision Medicine Webinar Series is powered by OncoLens. On a single, secure platform, OncoLens data science, informatics and advanced collaboration tools provide a first of a kind platform for targeted treatment planning and confident clinical decision making.

Watch Session Cases Individually

Case #1 — Recurrence after Chemoradiation
69 yo F p/w balance issues, left facial droop, and left leg weakness
Pathology: WHO grade 4 glioblastoma IDH-wildtype, MGMT unmethylated
Location: Right temporal lobe
Progression @ 1 year

Case #2 — Multifocal Glioblastoma
42 yo F p/w headache, generalized tingling, and facial numbness
Pathology: WHO grade 4 glioblastoma IDH-wildtype, MGMT unmethylated
Location: Lateral right frontal
Progression @ 6 months

Case #3 — BRAF-mutant Glioblastoma
67 yo F with showed seizures
Pathology: WHO grade 4 glioblastoma BRAF-V600E mutation
Location: Right temporoparietal
Progression @ 7 years after treatment holiday

Case #4 — Post-Radiation Changes
62 yo M p/w expressive aphasia
Pathology: c/w glioblastoma IDH-wildtype, MGMT methylated
Location: Left inferior temporal gyrus